Publikationen
1. Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells
Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN.
PLoS One. 2011;6(8):e23758. Epub 2011 Aug 18.
2. Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, Asslaber D, Tinhofer I, Greil R, Egle A.
Leukemia. 2011 May 24. [Epub ahead of print]
3. Chronische Lymphatische Leukämie (CLL) – Wann gilt das Konzept „watch & wait“ noch?
Egle A, Steinkirchner S.
Universum Innere Medizin. 04/11.
4. Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, Greil R, Tinhofer I.
Cancer Immunol Immunother. 2011 Jan;60(1):75-85. Epub 2010 Sep 21.
5. CLL-Therapie: Die tägliche Praxis.
Egle A
Krebs:Hilfe. 1:2011
6. Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.
Cancer. 2011 May 15;117(10):2163-9. doi: 10.1002/cncr.25752. Epub 2010 Nov 18
7. Raltegravir in pregnancy: a case series presentation.
Taylor N, Touzeau V, Geit M, Gisinger M, Egle A, Greil R, Rieger A, Zangerle R.
Int J STD AIDS. 2011 Jun;22(6):358-60.
8. Complete Remission of Waldenstrom Macroglobulinemia With Azacitidine and Rituximab.
Weiss L, Melchardt T, Neureiter D, Kemmerling R, Pleyer L, Greil R, Egle A, Moshir S.
J Clin Oncol. 2011 Jul 5. [Epub ahead of print]
9. Clinical aspects of 2009 pandemic influenza A (H1N1) virus infection in Austria.
Poeppl W, Hell M, Herkner H, Stoiser B, Fritsche G, Schurz-Bamieh N, Poeppl G, Gattringer R, Jones N, Maass M, Egle A, Burgmann H.
Infection. 2011 Aug;39(4):341-52. Epub 2011 May 5.
10. Therapie der chronisch lymphatischen Leukämie (B-CLL).
Steinkirchner S, Egle A.
Universum Innere Medizin. 09/11.
11. Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel O, Asslaber D, Piñón JD, Egle A, Greil R.
Cell Cycle. 2010 Jul 15;9(14):2764-8. Epub 2010 Jul 3.
12. Riding the 2-edged sword.
Egle A.
Blood. 2010 Jun 3;115(22):4325-6. Comment.
13. An uncommon cause of anaemia: Sheehan's syndrome.
Melchardt T, Namberger K, Weiss L, Egle A, Faber V, Greil R.
Wiener Klinische Wochenschrift. 2010 Dec 7.
14. Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation.
Labi V, Erlacher M, Krumschnabel G, Manzl C, Tzankov A, Pinon J, Egle A, Villunger A.
Genes & Development. 2010 Aug 1;24(15):1602-7.
15. microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R.
Blood. 2010 May 27;115(21):4191-7. Epub 2010 Jan 20.
16. MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber D, Pinon Hofbauer J, Greil R, Egle A.
Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.
17. Differenzierte Therapieansätze beim myelodysplastischen Syndrom.
Steinkirchner S, Melchardt T, Egle A.
JATROS Haematologie und Onkologie. 2010 Sep 20.
18. Neues bei follikulären Lymphomen.
Steinkirchner S, Egle A.
Universum Innere Medizin. 10/2010
19. Aminoglykoside - Eine tote Substanzklasse?
Egle A
JATROS Infektiologie. Jahrgang 4, Juli, 2/2010
20. Focus Onkologie: neues beim follikulären Lymphom.
Egle A
Universum Innere Medizin. 06/2010.
21. Differenzierte Therapieansätze beim myelodysplastischen Syndrom.
Steinkirchner S., Melchardt Th., Egle A.
JATROS Haematologie und Onkologie. 04/2010.
22. Aktuelle Therapie indolenter Non-Hodgkin-Lymphome.
Melchardt T, Egle A
Krebs:Hilfe. 3/2010, Seite 10-12.
23. B-CLL: Datenfülle zu Pathophysiologie und klinischem Management.
Egle A
JATROS Haematologie und Onkologie. 01/2010, Seite 80-82
24. Alemtuzumab (MabCampath®) – Wirksame Waffe in der Kombinationstherapie.
Egle A
SPECTRUM Onkologie. 4/10, S. 88.
25. PRIMA-Studie mit dem Anti-CD20-Antikörper Rituximab als Erhaltungstherapie – Neues beim follikulären Lymphom.
Steinkirchner S, Egle A.
Universum Innere Medizin. 06/10.
26. MDS - Krankheitsmodifizierende Therapieformen.
Egle A.
JATROS Haematologie und Onkologie. 2/2009 (S. 61 - 63).
27. PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Holler C, Piñón JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A.
Blood. 2009 Mar 19;113(12):2791-4. Epub 2009 Jan 23.
28. The molecular and cellular biology of chronic lymphocytic leukemia as the basis for novel therapeutic approaches.
Pleyer L, Egle A, Hartmann TN, Greil R.
Nature Clinical Practice Oncology. 2009 Jul;6(7):405-18. Epub 2009 Jun 2. Review.
29. Initial evaluation of the Roche COBAS TaqMan HIV-1 v2.0 assay for determining viral load in HIV-infected individuals.
Taylor N, Schmid I, Egle A, Greil R, Patsch W, Oberkofler H.
Antiviral Therapy. 2009;14(8):1189-93.
30. Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann TN, Pleyer L, Desch P, Egle A, Greil R.
Discovering Medicine. 2009 Oct;8(42):157-64. Review.
31. Bim and Bmf in tissue homeostasis and malignant disease.
Piñon JD, Labi V, Egle A, Villunger A.
Oncogene. 2008 Dec;27 Suppl 1:S41-52. Review.
32. Chronisch lymphatische Leukämie (CLL)-Auf dem Weg zur heilbaren Erkrankung
Egle A
Spectrum Onkologie 04/08
33. Follikuläres Lymphom.
Egle A.
in Lymphoproliferative Erkrankungen
R.Greil Uni-Med Science, 2007, Seite 93 - 107
34. The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Tinhofer I, Steurer M, Leitinger G, Rumpold H, Egle A, Erdel M, Greil R.
Haematologica-The Hematology Journal. 2006 Sep;91(9):1291-3.
35. Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer I, Rubenzer G, Holler C, Hofstaetter E, Stoecher M, Egle A, Steurer M, Greil R.
Blood. 2006 Nov 1;108(9):2950-6. Epub 2006 Jul 6.
36. Subversion of the Bcl-2 life/death switch in cancer development and therapy.
Adams JM, Huang CD, Strasser A, Willis S, Chen L, Wei A, van Delft M, Fletcher JI, Puthalakath H, Kuroda J, Michalak EM, Kelly PN, Bouillet P, Villunger A, O'Reilly L, Bath ML, Smidth DP, Egle A, Harris AW, Hinds M, Colman P, Cory S.
Cold Spring Harbor Symposia on Quantitative Biology. 2005;70:469-77.
37. VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia.
Egle A, Harris AW, Bath ML, O'Reilly L, Cory S.
Blood. 2004 Mar 15;103(6):2276-83. Epub 2003 Nov 20.
38. Bim is a suppressor of Myc-induced mouse B cell leukemia.
Egle A, Harris AW, Bouillet P, Cory S.
Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6164-9. Epub 2004 Apr 12.
39. Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.
Scott CL, Schuler M, Marsden VS, Egle A, Pellegrini M, Nesic D, Gerondakis S, Nutt SL, Green DR, Strasser A.
Journal of Cell Biology. 2004 Jan 5;164(1):89-96.
40. TNF cytokine family: more BAFF-ling complexities.
Labi Y, Egle A, Strasser A.
Curr Biol. 2001 Dec 11;11(24):R1013-6.
41. Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia: a comparison of three semiquantitation techniques
Marschitz I, Tinhofer I, Hittmair A, Egle A, Kos M, Greil R
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 113,219-229, 2000
42. Expression of functional Interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Tinhofer I, Marschitz I, Henn T, Egle A, Greil R
Blood, 2000 Jan 15;95(2):610-618.
43. Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas(Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Tinhofer I, Marschitz I, Egle A, Henn T, Villunger A, Greil R.
Blood. 1998 Jun 1;91(11):4273-81.
44. The role and significance of Fas(Apo-1/CD95) ligand (FasL) expression in immune priviledged tissues and cancer cells using multiple myeloma as a model
Greil R, Egle A, Villunger A
LEUKEMIA AND LYMPHOMA, Invited review, 31 (5-6), 477-490, 1998.
45. Functional granulocyte/macrophage colony stimulating factor receptor is constitutively expressed on neoplastic plasma cells and mediates tumour cell longevity.
Villunger A, Egle A, Kos M, Egle D, Tinhofer I, Henn T, Uberall F, Maly K, Greil R.
Br J Haematol. 1998 Sep;102(4):1069-80.
46. The Interleukin-1b-converting enzyme inhibitor crmA prevents Apo-1/fas- but not glucocorticoid-induced ADP(Ribosyl)transferase cleavage and apoptosis in lymphoblastic leukemia cells
Geley S, Hartmann L, Kapelari K, Egle A, Villunger A, Heidacher D, Greil R, Auer B, Kofler R
FEBS LETTERS, 402,36-40, 1997
47. Expression of Apo-1/Fas (CD95), Bcl-2, Bax and Bcl-x in myeloma cell lines: relationship between responsiveness to anti-Fas mab and p53 functional status.
Egle A, Villunger A, Marschitz I, Kos M, Hittmair A, Lukas P, Grünewald K, Greil R.
Br J Haematol. 1997 May;97(2):418-28.
48. Constitutive expression of Fas (Apo-1/C95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance
Villunger A, Egle A, Marschitz A, Kos M, Böck G, Ludwig H, Geley S, Kofler R, Greil R:
BLOOD, 1997, 90, 12-20. [Rapid Publication]
49. Fludarabin-induced apoptosis is mediated via Caspase I but is independent from Fas (Apo-1/CD95) signaling in T-acute lymphatic leukemia cells.
Villunger A, Egle A, Kos M, Böck G, Hartmann B, Geley S, Kofler R, Greil R
CANCER RESEARCH, 1997, 57, 3331-3334. [Advances in Brief]
50. Constituents of autocrine IL-6 loops in myeloma cell lines and their targeting for neoplastic growth by antibody strategies
Villunger A, Egle A, Kos M, Hittmair T, Maly K, Greil R
INTERNATIONAL JOURNAL CANCER,65, 498-505, 1996
51. Effect of 2`, 2`- difluorodeoxycytidine (Gemcitabine) on myeloma cell lines resistant to steroids
Gruber J, Geisen F, Sgonc R, Egle A, Villunger A, Boeck G, Konwalinka G, Greil R
STEM CELLS, 14, 351-362, 1996
52. IL-10 serum levels in B-cell chronic lymphocytic leukaemia.
Egle A, Marschitz I, Posch B, Herold M, Greil R.
Br J Haematol. 1996 Jul;94(1):211-2.
53. Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha 2.
Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R.
Eur J Immunol. 1996 Dec;26(12):3119-26.